What is inside a NixMen capsule

Seven actives, 815 mg of plant material and one amino acid, plus 30 IU of vitamin E. Below is every one of them with its weight, its Latin name, the name a Hakeem would use, and what the published work does and does not support.

Actives: 7
Per capsule: 815 mg
From the Unani pharmacopoeia: 4 of 7
Capsules per jar: 30

Start with the reason this page exists. Hamdard sells Gulmundene for frequent urination in men over forty and does not print what is in it. Ajmal sells Ghadudi for enlarged prostate and does not print what is in it. Prolan asks between six and eleven thousand rupees and does not print what is in it.

A man handing over ten thousand rupees ought to be able to read the label and then read up on every line of it. So here is the label, and then the reading.

The label, per capsule

Weights are per capsule, not per serving, and not per jar. One capsule daily is the full dose.

Active	Per capsule	Unani name and class	What it is doing here
Tribulus Terrestris extract Khar-e-Khasak Khurd · Gokhru	350 mg	Mudirr-e-Baul — the diuretic class of the Unani pharmacopoeia	Protodioscin makes the vessel wall respond more strongly to nitric oxide. Measured on tissue: relaxation to acetylcholine up 10 per cent, to nitroglycerine up 24 per cent, after eight weeks of oral dosing.
Withania Somnifera Asgand Nagori	300 mg	Muqawwi — the tonic class of the Unani pharmacopoeia	The stress axis. In 64 people over 60 days, cortisol fell 27.9 per cent against 7.9 per cent on placebo. Lower cortisol means smooth muscle that is not being held tense around the clock.
Asphaltum Punjabianum Salajeet	50 mg	Classically used for genito-urinary complaints across this region	Fulvic acids and dibenzo-alpha-pyrones. Protects mitochondrial function and cuts oxidative load — malondialdehyde in seminal fluid down 18.7 per cent over 90 days. Purified and batch-tested for heavy metals.
L-Arginine	50 mg	—	The amino acid the body builds nitric oxide from. A modern addition with no Unani history, and we are not going to invent one for it.
Panax Ginseng extract Jinseng	50 mg	Not a classical Unani drug — an East Asian plant that entered South Asian dispensaries in the last century	The only ingredient in this formula with a human trial on urinary symptoms: IPSS significantly better than placebo at week six and week twelve. Ginsenosides switch on the enzyme that produces nitric oxide.
Vitamin E	30 IU	—	Thirty IU is roughly the daily requirement for an adult man — deliberately, because it keeps the dose thirteen times below the 400 IU that raised prostate cancer risk in the SELECT trial.
Crocus Sativus Zafran	15 mg	Mudirr-e-Baul and Muqawwi-e-Qalb — diuretic and heart tonic. Ibn Sina wrote about it.	Crocin and safranal relax smooth muscle and carry antioxidant activity. Fifteen milligrams sits at the low end of the studied range, and it is here for the mechanism rather than the headline.

815 mg of actives plus 30 IU vitamin E. Capsule shell is plant-based — nothing of animal origin goes into it.

Three pathways, not one claim

Every prostate supplement sold in this country leans on the same sentence: it blocks 5-alpha reductase, so it lowers DHT, so the gland behaves. It is a good sentence. It is also, for herbal formulas, unsupported in human beings.

Tribulus was put through a screen of eleven herbs specifically to test 5-alpha reductase inhibition and did not make the shortlist. Ginseng does down-regulate the enzyme — in rats. In the one human trial where ginseng moved urinary symptoms, testosterone and DHT did not budge at all. So whatever was working there, it was not the androgen story.

What our formula does reach falls into three groups, and explaining those properly is more use to you than a sentence we cannot stand behind.

One: the nitric oxide pathway

The bladder neck and the prostatic urethra are wrapped in nerves that release nitric oxide, and nitric oxide is the signal that lets that muscle relax. This is the dynamic half of the obstruction — the half that alpha blockers work on, and the half that moves in days rather than months.

1
L-Arginine, 50 mg — the substrate
Nitric oxide is built from arginine. That is all this ingredient does here, and we will be straight about the dose: the trials that showed an effect on erectile function used 1,500 to 5,000 mg a day. Fifty milligrams is a fraction of that and a fraction of what you get from a plate of daal. It is in the formula as part of the pathway, not as the engine.
2
Panax Ginseng extract, 50 mg — the switch
Ginsenosides induce the enzyme that produces nitric oxide in the vessel wall. Ginseng is also the only ingredient in this formula with a human trial on urinary symptoms: 88 men aged 40 to 75, twelve weeks, and the IPSS score — residual urine, frequency, intermittency, urgency, weak stream, straining, night trips — came out significantly better than placebo at week six and held at week twelve. That trial used red ginseng oil, a different form from ours, and a higher dose — which is the caveat, and we would rather print it than hope you miss it.
3
Tribulus Terrestris extract, 350 mg — the amplifier
Protodioscin, the active in Tribulus, makes the vessel wall respond more strongly to nitric oxide. Measured directly on tissue after eight weeks of oral dosing: relaxation to acetylcholine up 10 per cent, to nitroglycerine up 24 per cent. Remove the endothelium or block nitric oxide synthase and the effect disappears — which is how we know the pathway is the mechanism. What Tribulus does not do is raise testosterone; a meta-analysis of eight trials found no difference from placebo.

These three have been tested together

A trial on 98 men used exactly this combination — protodioscin, ginsenosides and L-arginine in one tablet — for three months. Every IIEF-5 parameter improved, and the difference against control was significant in the men who were not diabetic. In the diabetic group there was no difference from placebo. That is the kind of detail most labels leave out.

Two: cortisol and the stress axis

A man getting up three times a night is sleeping in ninety-minute pieces, and broken sleep pushes cortisol up. High cortisol keeps smooth muscle tense. The symptom feeds the thing that makes the symptom worse, and that loop is why some men get steadily worse without anything new happening in the gland.

1
Withania Somnifera, 300 mg — Asgand Nagori
The best-documented herb in the world for this loop. Sixty-four people, sixty days, 300 mg twice daily: cortisol down 27.9 per cent from baseline against 7.9 per cent on placebo. A separate 16-week crossover in 57 men aged 40 to 70 put salivary testosterone up 14.7 per cent and DHEA-S up 18 per cent against placebo. In that same trial, self-reported energy and sexual wellbeing did not separate from placebo — so we are quoting the hormone result as a hormone result, nothing more.
2
Asphaltum Punjabianum, 50 mg — Salajeet
Works the same axis and protects the mitochondria that broken sleep has been draining. In 75 healthy men aged 45 to 55 on purified Salajeet for 90 days, total testosterone, free testosterone and DHEA-S all rose significantly while LH and FSH stayed in range. You will see a figure of “20 per cent” attached to that study across the internet. It is not in the paper. We are not going to repeat it.

Three: oxidative load — and the metal problem nobody mentions

Tissue that has been working for fifty years carries more oxidative damage than it clears. Salajeet dropped malondialdehyde — the standard marker — by 18.7 per cent in seminal fluid over 90 days in men with low sperm counts. Zafran and vitamin E cover the same ground from the antioxidant side.

Now the part that matters more than any of that. In 2024, scientists at PCSIR Lahore tested Salajeet samples and found roughly 65 metals in them, lead, arsenic, cadmium and mercury among them. Some samples sat inside WHO limits. Others did not. Their conclusion was blunt: taking Salajeet without knowing its metal content is not safe.

Both clinical studies on Salajeet used purified material. So does NixMen — purified, and tested batch by batch before it goes near a capsule. The sticky black lump sold by weight in a bazaar is a different product with the same name, and this is the single biggest reason our jar costs what it does.

On vitamin E we made the opposite kind of decision. Thirty IU is roughly a grown man’s daily requirement — thirteen times below the 400 IU that raised prostate cancer risk in the SELECT trial across 35,533 men. We put it in at the physiological dose deliberately, and we are not going to tell you it protects anybody from anything.

Seven actives, 815 mg, one capsule a day

Thirty capsules, Rs 10,900, free delivery all over Pakistan. Our agent calls you before anything is dispatched.

Rs 10,900 Rs 21,800

Order at Rs 10,900

The doses, against the research

We have not seen another supplement in Pakistan publish this table, and you will see why in the right-hand column. Read it anyway — you should know what you are taking.

Active	In NixMen	In the trials	What that means
Withania Somnifera	300 mg	600–675 mg/day	Half the studied dose
Tribulus Terrestris	350 mg	1,500 mg/day	Under a quarter
Asphaltum Punjabianum	50 mg	200–500 mg/day	A tenth to a quarter
Crocus Sativus	15 mg	15–200 mg	At the bottom of the studied range
Panax Ginseng	50 mg	2,700 mg/day of root	Extract, so not directly comparable — but low
L-Arginine	50 mg	1,500–5,000 mg/day	Far below; present as part of the pathway
Vitamin E	30 IU	RDA 15 mg	At the daily requirement, by design

A formula is a set of compromises inside one capsule. Seven actives at trial doses would be a handful of tablets a day and nobody would take them. What we would not do is print the trial results and hide the doses, which is the standard practice in this category.

Before you take it

On warfarin, or a blood thinner

Ginseng interacts with warfarin, and vitamin E works against vitamin K clotting. Speak to your doctor first.

Diabetic and on tablets or insulin

Ginseng can add to the glucose-lowering effect. Worth telling the doctor who manages your sugar.

Thyroid trouble

Ashwagandha can nudge T4 upward. If you are on levothyroxine or have an overactive thyroid, ask first.

Surgery booked

Stop two weeks before any planned operation. Standard practice with vitamin E.

Order NixMen

One month, 30 capsules, Rs 10,900. Cash on delivery, free anywhere we ship.

30 capsules · One month course
Karachi · Lahore · Rawalpindi · Islamabad · Multan
Rs 10,900 · In stock

Questions we get on the phone

Is NixMen halal?

Yes. Seven plant and nutrient actives in a plant-based capsule shell. No gelatin, nothing of animal origin at any stage.

Which ingredient does the actual work?

If you want one name: ginseng, because it is the only one in the formula with a human trial on urinary symptoms. If you want the honest answer: the three that feed the nitric oxide pathway do so together, and they have been tested together.

Is the Salajeet real Gilgit Salajeet?

It comes from Gilgit-Baltistan, and it is purified and tested for lead, arsenic, cadmium and mercury before it goes into a capsule. That testing is the difference between our Salajeet and the kind sold loose by weight.

Does it contain saw palmetto?

No. Saw palmetto is the single herb most of the Pakistani supplements are built on, and it is a reasonable ingredient. We went a different way: three actives on the nitric oxide pathway, two on the stress axis, two on oxidative load.

Will it raise my testosterone?

Ashwagandha and Salajeet each moved testosterone in their own trials, at doses higher than ours. Tribulus did not — eight randomised trials, no difference from placebo. We would not buy this jar expecting a hormone result.

Any side effects?

At these doses, uncommon. The interactions worth knowing are listed above — warfarin, diabetes tablets, thyroid medicines, and planned surgery. If you take any of those, ask your doctor before you start rather than after.